Characterization of molecular events in the pathogenesis and development of breast cancer.
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Characterization of molecular events in the pathogenesis and development of breast cancer. by Susan Jane Done

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Published .
Written in English


Book details:

The Physical Object
Pagination220 leaves.
Number of Pages220
ID Numbers
Open LibraryOL20386915M
ISBN 100612537765

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Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple histological subtypes. Molecular diversity has been shown to occur within specific histological subtypes of epithelial ovarian cancer, between different tumors of an individual patient, as well as within individual tumors. Recent advances in the molecular characterization of epithelial ovarian Cited by: Rather, this chapter will focus on the molecular pathogenesis of prostate cancer. Incidence and Etiology of Prostate Cancer. Risk factors for development of prostate cancer include age, race, inherited genes, and environmental factors (such as diet),,,.Cited by: 1.   The development of breast cancer entails multiple events; unfortunately, the two main factors elucidated in the experimental animal model, the causative agent and the time of initiation, are unknown in the human population (47,48).Cited by: Thyroid cancer is a common endocrine malignancy that has rapidly increased in global incidence in recent decades 1, the United States, the average annual increase in thyroid cancer incidence of % between and is the highest among all cancers gh the death rate of thyroid cancer is relatively low, the rate of disease recurrence or persistence is high, Cited by:

characterization of the genes involved in breast cancer initiation and progression, including invasion and metastasis, will facilitate study of the basic physiology and biochemistry of the normal breast, because it will become possible to assess the role of these genes in normal breast development and function. Breast cancer and Hormonal contraceptives: collaborative reanalysis of individual data on 53, women with breast cancer and , women without breast cancer from 54 .   The year marks exactly two decades since HER2 was functionally implicated in the pathogenesis of human breast cancer (). This finding established the HER2 oncogene hypothesis for the development of some human cancers. The subsequent two decades have Cited by:   Introduction. Gastric cancer is a global health problem of major proportions. In , cancer of the stomach was the most frequent neoplasm in the world, comprising % of the major cancers with ~ incident cases per year (1).In the mid s, gastric cancer was surpassed by lung cancer, with stomach comprising and lung % of estimated incident Cited by:

  Thyroid cancer is a common endocrine malignancy. There has been exciting progress in understanding its molecular pathogenesis in recent years, as best exemplified by the elucidation of the Cited by: Abstract. Over the last 20 years, there have been major advances in the treatment and prevention of breast cancer (BC), including the development and widespread use of mammography to detect cancer at an early stage, and the use of adjuvant chemotherapy or hormonal therapy to treat these early cancers to improve by: The book starts off by describing the normal breast tissue and continues with information on the development of breast cancer, as well as laboratory models (such as transgenic mice) used to study it. The last chapter includes personal research that the authors have performed in the field and potential clinical implications that it may : $ His research focuses on the study of the molecular pathogenesis of endometrial cancer, the most common gynecological cancer in women. Current projects in the lab are examining the molecular differences between aggressive and non-invasive endometrial cancers, gene methylation patterns in endometrial cancer, and the characterization of novel.